Site‐Selective C–H/C–H Cross Dehydrogenative Coupling Between Quinoxalin‐2(1H)‐Ones and Aliphatic Nitriles

An efficient and facile method was developed for the synthesis of C3‐cyanoalkylated quinoxalin‐2(1H)‐ones via a C–H/C–H cross dehydrogenation coupling between quinoxalin‐2(1H)‐ones and aliphatic nitriles. The method enables the β‐ or γ ‐site‐selective C−H activation of aliphatic nitriles, giving the corresponding products in moderated to good yields. The reaction demonstrated a broad substrate scope and useful synthetic application ability.