Why the study?
Does antihypertensive treatment prevent resistance artery remodeling in hypertensive patients with type 2 diabetes compared to untreated hypertensives and normotensives?
Does antihypertensive treatment prevent resistance artery remodeling in hypertensive patients with type 2 diabetes compared to untreated hypertensives and normotensives?
Despite effective diastolic blood pressure control with antihypertensive treatment, resistance arteries from hypertensive diabetic patients show marked remodeling that exceeds that of untreated nondiabetic hypertensives.
Authors
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Antihypertensive therapy may not normalize resistance artery structure in diabetes; hypothesis-generating for diabetes-specific vascular interventions in prospective trials.
Endemann et al. (2004) studied this question.
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