Why the study?
Does oral contraceptive use increase the risk of myocardial infarction and coronary heart disease in women?
Population
Women at risk for or with myocardial infarction and coronary heart disease
Comparison
Oral contraceptives and estrogen use vs Non-users of oral contraceptives
Design
Review
Authors
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Warrants caution with oral contraceptive prescribing in older or smoking women; leaves open absolute risks with modern low-dose regimens.
Does oral contraceptive use increase the risk of myocardial infarction and coronary heart disease in women?
This review highlights that oral contraceptive use, especially combined with smoking and advancing age, significantly increases the risk of myocardial infarction and circulatory death in women.
Johansson et al. (1983) studied this question.