Why the study?
BNP levels facilitate HF diagnosis and predict mortality in chronic systolic HF, but their ability to predict in-hospital mortality in acute decompensated HF was unclear.
Does admission B-type natriuretic peptide (BNP) level predict in-hospital mortality in patients with acute decompensated heart failure?
Does admission B-type natriuretic peptide (BNP) level predict in-hospital mortality in patients with acute decompensated heart failure?
Elevated admission BNP levels independently predict in-hospital mortality in patients with acute decompensated heart failure, regardless of whether systolic function is reduced or preserved.
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May aid risk stratification in acute decompensated HF; extends BNP prognostic value but leaves open role in guiding care.
Fonarow et al. (2007) studied this question.
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