What question did this study set out to answer?

To evaluate the benefits of endovascular thrombectomy in patients experiencing neurological deterioration from mild large vessel occlusion beyond 24 hours after last known well.

May 6, 2026

Thrombectomy for Mild Large Vessel Occlusion With Neurological Deterioration Beyond 24 h From Last Known Well.

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Authors

RRRekefu RehemanPeople's Hospital of Xinjiang Uygur Autonomous Region GBGuosen BuXinjiang Medical University YLY L LiPeople's Hospital of Xinjiang Uygur Autonomous Region

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Implication

Randomized trial demonstrates improved functional outcomes in mild large vessel occlusion patients despite increased hemorrhage risk.

Key Points

To evaluate the benefits of endovascular thrombectomy in patients experiencing neurological deterioration from mild large vessel occlusion beyond 24 hours after last known well.
Identified consecutive patients with mild large vessel occlusion at four centers
Grouped patients by treatment: thrombectomy versus medical management
Used inverse probability of treatment weighting to adjust baseline characteristics.
Ninety-day functional independence was achieved in 44.6% of EVT patients compared to 16.7% in medical management patients (adjusted OR 3.60, 95% CI 1.62-7.99).
Rate of hemorrhagic transformation was higher in the EVT group (19.6% vs 6.0%; adjusted OR 3.72, 95% CI 1.05-13.20).
Sensitivity analysis indicated EVT was associated with a greater likelihood of functional independence (adjusted OR 2.65, 95% CI 1.08-6.49).

Cite This Study

Reheman et al. (2026) studied this question.

synapsesocial.com/papers/69fadad703f892aec9b1e8a2 https://doi.org/10.1016/j.acra.2026.04.020

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Thrombectomy for Mild Large Vessel Occlusion With Neurological Deterioration Beyond 24 h From Last Known Well.

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Key Points

Cite This Study

Thrombectomy for Mild Large Vessel Occlusion With Neurological Deterioration Beyond 24 h From Last Known Well.

Discussion

Member takes

Implication

Key Points

Cite This Study

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