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The study examines the relationship between circadian rhythm and the timing of ischemic stroke onset.

Circadian Rhythm and Ischemic Stroke: A Hospital-based Study in Shanghai, China

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The study examines the relationship between circadian rhythm and the timing of ischemic stroke onset.
Analyzed electronic medical records from Shanghai East Hospital for 2021 and 2022.
Screened 1,320 patients, with 406 meeting inclusion criteria.
Categorized stroke occurrences into six time intervals for analysis using Cosinor and chi-square tests.
Stroke occurrences peaked between 08:00 and 11:59, representing 36.2%.
75.9% of strokes occurred during daylight hours.
Hypertension and diabetes were not significantly associated with stroke timing.

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Observational study shows circadian rhythm affects ischemic stroke timing in Shanghai, suggesting new preventive strategies.

Singh et al. (2026) studied this question.

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