Anxiety and Risk of Incident Coronary Heart Disease
Why the study?
Less research has focused on the association of anxiety with incident CHD compared to other negative emotions such as depression.
Does anxiety increase the risk of incident coronary heart disease and cardiac mortality in initially healthy persons?
Comparison
Baseline anxiety vs no anxiety
Design
Meta-analysis of prospective cohort studies
Follow-up
Mean 11.2 years
Authors
Discussion
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Member takes
Implication
Anxiety not yet a target for CHD prevention in practice; leaves open its causal role and treatment benefit.
Structured PICO
Does anxiety increase the risk of incident coronary heart disease and cardiac mortality in initially healthy persons?
P
Population
20 prospective studies comprising 249,846 initially healthy persons (nonpsychiatric cohorts) with anxiety assessed at baseline
I
Intervention
Presence of anxiety (assessed at baseline)
C
Comparator
Absence of anxiety (non-anxious persons)
O
Outcome
Incident coronary heart disease (CHD)hard clinical
Anxiety is an independent risk factor for incident coronary heart disease and cardiac mortality in initially healthy individuals.
Cite This Study
Roest et al. (2010) studied this question.