Why the study?
Does a prolonged QTc interval predict mortality in patients with heart failure and BNP levels >400 pg/mL?
Population
241 patients with heart failure who had BNP levels >400 pg/mL
Comparison
Prolonged QTc interval (>440 ms) vs Normal QTc interval
Design
Cohort
Follow-up
6 months
Authors
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Prolonged QTc may aid mortality risk stratification in advanced HF; leaves open whether QTc modification improves outcomes.
Does a prolonged QTc interval predict mortality in patients with heart failure and BNP levels >400 pg/mL?
A prolonged QTc interval (>440 ms) is a strong, independent predictor of mortality in patients with advanced heart failure and elevated BNP levels.
Vrtovec et al. (2003) studied this question.
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