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September 28, 2022Catheterization and Cardiovascular Interventions

Extraplaque versus intraplaque tracking in chronic total occlusion percutaneous coronary intervention

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Why the study?

The impact of modern dissection and reentry techniques on the long-term outcomes of CTO PCI remains controversial.

Does extraplaque tracking compared to intraplaque tracking affect clinical outcomes in patients undergoing chronic total occlusion percutaneous coronary intervention?

Population

2982 patients across seven observational studies undergoing CTO PCI

Comparison

Extraplaque tracking vs intraplaque tracking

Design

Systematic review and meta-analysis

Follow-up

Median follow-up of 12 months (range 9-12 months)

Authors

MMMichael MegalyInterventional CardiologyKBKevin BudaCross-Cutting CardiologyJKJudit KarácsonyiUniversity of Utah

Discussion

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Member takes

Overview

May warrant preferring IP tracking in CTO PCI when feasible; leaves open whether RCTs will confirm these observational associations.

Structured PICO

Does extraplaque tracking compared to intraplaque tracking affect clinical outcomes in patients undergoing chronic total occlusion percutaneous coronary intervention?

P
Population
2,982 patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) pooled from 7 observational studies
I
Intervention
Extraplaque (EP) tracking during CTO PCI
C
Comparator
Intraplaque (IP) tracking during CTO PCI
O
Outcome
Major adverse cardiovascular events (MACE) at median 12 months follow-upcomposite

Extraplaque tracking in CTO PCI is associated with a higher risk of MACE and TVR at 1 year compared to intraplaque tracking, likely driven by greater baseline lesion complexity.

Cite This Study

Megaly et al. (2022) studied this question.

synapsesocial.com/papers/69fcc0f94f95092fbe78fbd9https://doi.org/10.1002/ccd.30403
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Culotte stenting for coronary bifurcation lesions with 2nd and 3rd generation everolimus-eluting stents: the CELTIC Bifurcation Study2018 · 19 citations
  2. 2Treating chronic total occlusions using subintimal tracking and reentry: The STAR Technique2005 · 274 citations
  3. 3A Novel Algorithm for Treating Chronic Total Coronary Artery Occlusion2019 · 93 citations