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May 8, 2026CureusOpen Access

Fatal Presumed Rhino-Orbito-Sinus Mucormycosis in a Child With Fanconi Anemia: A Case Report

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Authors

SCSoufia CharafSBSanaa BouramdaneKEKenza Elmkeddam

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Overview

Case report reveals fatal mucormycosis in a child with Fanconi anemia, highlighting diagnostic challenges and critical management issues.

Key Points

  • This report discusses the rapid progression and challenges in diagnosing mucormycosis in a child with Fanconi anemia.
  • Case report of a 10-year-old male patient with bone marrow aplasia and febrile tonsillitis.
  • Liposomal amphotericin B was administered; surgical debridement was delayed due to severe thrombocytopenia.
  • Imaging techniques were used to assess the extent of infection.
  • Patient presented with necrotic palatal lesions and orbital extension of infection.
  • Despite treatment with liposomal amphotericin B, the patient required intensive care and eventually died.
  • Emphasis on the importance of early antifungal therapy in severely immunocompromised patients.

Cite This Study

Charaf et al. (2026) studied this question.

synapsesocial.com/papers/69fd7ddcbfa21ec5bbf060a2https://doi.org/10.7759/cureus.108313
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