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The aim is to evaluate whether stroke risk scores reflect underlying brain health and asymptomatic vascular injury.

Abstract Number: Esoc2026a694 Vascular Brain Injury and Stroke Risk Scores: Cross-Sectional Neuroimaging Analysis in a Healthy Cohort

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The aim is to evaluate whether stroke risk scores reflect underlying brain health and asymptomatic vascular injury.
Analyzed 293 healthy adults using stroke risk assessments and MRI scans.
Evaluated imaging biomarkers including brain parenchymal fraction, white matter hyperintensity, and cerebral microbleeds.
Used linear and logistic regression to assess relationships, adjusting for vascular risk factors.
Higher QStroke scores linked to lower brain parenchymal fraction (β=-0.016 to -0.017) and greater white matter hyperintensity (β=1.57 to 1.60).
Cerebral microbleeds and silent infarcts showed increased odds (OR=2.33 to 2.68; p<0.001).
Similar patterns observed with ten-year rFSRP, indicating consistent associations across age groups.

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Cross-sectional analysis reveals stroke risk scores reflect both future stroke risk and asymptomatic vascular injury in a healthy cohort.

Kasemsantitham et al. (2026) studied this question.

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