Why the study?
Does primary aldosteronism cause greater adverse changes in left ventricular anatomy and function compared to essential hypertension?
Does primary aldosteronism cause greater adverse changes in left ventricular anatomy and function compared to essential hypertension?
Primary aldosteronism is associated with greater left ventricular hypertrophy and diastolic dysfunction compared to matched essential hypertension, and these changes appear reversible after surgical removal of aldosterone-producing tumors.
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May prompt earlier PA screening in hypertensives with LVH; leaves open causal role and reversibility.
Rossi et al. (1996) studied this question.
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