Why the study?
For patients with acute STEMI who miss the optimal time window, optimal management remains controversial.
Does immediate PCI reduce adverse clinical outcomes in elderly patients with acute STEMI presenting > 12 hours after symptom onset?
Does immediate PCI reduce adverse clinical outcomes in elderly patients with acute STEMI presenting > 12 hours after symptom onset?
In elderly patients presenting with STEMI >12 hours after symptom onset, immediate PCI does not appear to reduce adverse clinical outcomes compared to other timing strategies.
Immediate PCI should not be routine for elderly late-presenting STEMI; challenges assumptions favoring early revascularization beyond 12 hours.
Introduction: Primary percutaneous coronary intervention (PPCI) is an effective method for the clinical treatment of acute ST-segment elevation myocardial infarction (STEMI). For patients who miss the optimal time window, optimal management of these patients remains controversial. Aim: To compare the effects of different timing of percutaneous coronary intervention on the long-term prognosis of elderly patients with acute ST-segment elevation myocardial infarction (STEMI) with time from symptom onset > 12 hours. Material and methods: = 80). Primary study end points were 12-month cardiac mortality, nonfatal myocardial infarction (MI), target-vessel revascularization, and heart failure-related rehospitalization. Conclusions: For acute STEMI patients who missed the optimal time of PCI, immediate PCI did not reduce adverse clinical outcomes.
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Jia et al. (2024) studied this question.
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