Evaluation of Antioxidant Status in the Liver, Kidney, and Heart of Formalin-Induced Wistar Rats Treated with Alstonia boonei Extracts

May 5, 2026

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Key Points

This research aims to evaluate the antioxidant effects of Alstonia boonei extracts on liver, kidney, and heart tissues in rats exposed to formalin.
Formalin-induced oxidative stress was induced in Wistar rats.
Alstonia boonei extracts were administered to assess antioxidant status.
Biochemical analyses of liver, kidney, and heart tissues were performed post-treatment.
Alstonia boonei extracts showed significant improvements in antioxidant enzyme levels in the liver (p<0.05).
A marked reduction in oxidative stress markers was observed in the kidney (p<0.01).
Heart tissues exhibited enhanced antioxidant status compared to the control group (p<0.05).

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Evaluates antioxidant effects of Alstonia boonei in formalin-induced Wistar rats, indicating potential liver, kidney, and heart protection.

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Osadolor et al. (2026) studied this question.

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