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May 1, 2026HLA

Identification of the Full Genomic Sequence of the HLA‐DRB1*13:370N Allele by Next Generation Sequencing

Myriam Dollerschell Cécilia Da Costa Judith Desoutter Julien Lion Nicolas Guillaume

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Key Points

The aim is to identify the complete genomic sequence of the HLA-DRB1*13:370N allele.
Utilized next generation sequencing techniques to analyze the allele.
Focused on nucleotides in exon 2 for specific mutations.
Identified a two-nucleotide deletion in exon 2 of the HLA-DRB1*13:370N allele compared to HLA-DRB1*13:01:01:01.

Implication

Identifies novel genomic sequence in HLA-DRB1 allele, suggesting implications for genetic research.

Abstract

HLA-DRB1*13:370N differs from the HLA-DRB1*13:01:01:01 allele by a deletion of two nucleotides in exon 2.

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Cite This Study

Dollerschell et al. (2026) studied this question.

synapsesocial.com/papers/69fed0e2b9154b0b82877f60 https://doi.org/10.1111/tan.70747

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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