Population
Patients with diagnosed diabetic nephropathy (n=34) and normal kidneys (n=12)
Design
Case-control
Authors
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Hypothesis-generating for lipid accumulation in diabetic nephropathy pathogenesis; requires prospective validation before clinical consideration.
Altered renal lipid metabolism and lipid accumulation occur in human diabetic nephropathy and correlate with glomerular filtration rate and inflammation, suggesting a role in pathogenesis.
Herman‐Edelstein et al. (2013) studied this question.
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