Why the study?
Does autologous bone marrow-derived stem cell transplantation improve left ventricular function and reduce myocardial lesion area in patients with acute myocardial infarction?
Does autologous bone marrow-derived stem cell transplantation improve left ventricular function and reduce myocardial lesion area in patients with acute myocardial infarction?
Autologous bone marrow stem cell transplantation in AMI patients significantly improves surrogate imaging markers like LVEF and LVESV, though adequately powered trials are needed to confirm clinical outcome benefits.
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Bolsters stem cell evidence on LV imaging surrogates in AMI; leaves open translation to clinical outcomes.
Martin‐Rendon et al. (2008) studied this question.
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