What question did this study set out to answer?

To investigate the incidence and prognostic significance of fasting hyperglycemia in patients presenting with a first myocardial infarction.

August 1, 1991Diabetes Care

In-Hospital Prognosis of Ppatients With Fasting Hyperglycemia After First Myocardial Infarction

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Why the study?

Does fasting hyperglycemia worsen in-hospital prognosis in patients with a first myocardial infarction?

Population

752 patients with a first myocardial infarction

Comparison

Fasting hyperglycemia or previously known… vs Normal fasting blood glucose

Design

Cohort

Follow-up

in-hospital

Authors

JOJohn O’SullivanUniversity College Dublin RCRonán ConroyPreventive Cardiology KRKillian RobinsonGeneral / Preventive / Lipids

Discussion

Member takes

Implication

Fasting hyperglycemia flags high-risk first-MI patients; leaves open whether glucose intervention improves outcomes.

Key Points

To investigate the incidence and prognostic significance of fasting hyperglycemia in patients presenting with a first myocardial infarction.
Measured blood glucose levels after an 8-hour overnight fast in 752 patients hospitalized with a first myocardial infarction.
Stratified patients into three groups: normal fasting blood glucose (92.5%), fasting hyperglycemia without prior history of glucose intolerance (3%), and known diabetes mellitus (4.5%).
Patients with fasting hyperglycemia were significantly older and experienced significantly more in-hospital complications compared to the normal blood glucose group.
Outcomes and mean age showed no significant difference between patients with newly detected fasting hyperglycemia and those with established diabetes mellitus.
The poorer in-hospital prognosis in fasting hyperglycemic patients was not associated with larger infarct size as measured by peak cardiac enzyme levels.

Structured PICO

Does fasting hyperglycemia worsen in-hospital prognosis in patients with a first myocardial infarction?

Population

752 patients with a first myocardial infarction

Intervention

Fasting hyperglycemia (no prior history of glucose intolerance) or previously known diabetes mellitus

Comparator

Normal fasting blood glucose

Outcome

In-hospital complications and prognosishard clinical

Fasting hyperglycemia detected after a first myocardial infarction is associated with a poor in-hospital prognosis, identifying a high-risk group.

Cite This Study

O’Sullivan et al. (1991) studied this question.

synapsesocial.com/papers/69ffccc67955d29dc3260fb5 https://doi.org/10.2337/diacare.14.8.758

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In-Hospital Prognosis of Ppatients With Fasting Hyperglycemia After First Myocardial Infarction

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

In-Hospital Prognosis of Ppatients With Fasting Hyperglycemia After First Myocardial Infarction

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider