Key result
Fasting hyperglycaemia linked to ~8-fold greater risk of in-hospital acute LVF after AMI.
Why the study?
Patients with recent myocardial infarction have an increased incidence of impaired fasting glucose and new-onset diabetes, with elevated fasting glucose linked to increased morbidity and mortality.
Does fasting hyperglycaemia predict worse outcomes in patients with acute myocardial infarction?
Population
102 patients with first attack acute myocardial infarction
Comparison
Fasting hyperglycaemia vs fasting euglycaemia
Design
Case-control study
Follow-up
30 days
Authors
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May identify AMI patients needing closer HF surveillance; hypothesis-generating for glucose-control trials.
Cohort (n=102)
No
Does fasting hyperglycaemia predict worse outcomes in patients with acute myocardial infarction?
Odds Ratio: 8.286 (95% CI 3.137–21.883)
Absolute Event Rate: 56.9% vs 13.7%
p-value: p=<0.001
Fasting hyperglycaemia is a significant predictor of in-hospital heart failure and 30-day cardiovascular mortality following a first acute myocardial infarction.
Shofiullah et al. (2016) conducted a cohort in Acute myocardial infarction (n=102). Fasting hyperglycaemia vs. Fasting euglycaemia was evaluated on In-hospital acute left ventricular failure (OR 8.286, 95% CI 3.137-21.883, p=<0.001). Fasting hyperglycaemia significantly increased the risk of developing in-hospital acute left ventricular failure compared to euglycaemia in patients with acute myocardial infarction (OR 8.286).
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