Shows successful one-pot synthesis of 2-acylpyrroles in a variety of conditions, indicating broad applicability.
]pyrrol-4-ones through silver/base promoted tandem reactions of intramolecular hydroalkylation and oxidation of propargylamines has been developed successfully. The strategy has the advantages of one-pot synthesis, easily available raw materials, good atomic economy, wide functional group tolerance, and excellent regioselectivity. Moreover, this method can also be used to construct 2-acylfuran, further expanding its applicability.
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Yi et al. (2026) studied this question.
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