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This research examines the virulence and antibiotic resistance profiles of Klebsiella pneumoniae strains isolated from urinary tract infections.

May 11, 2026BMC UrologyOpen Access

Virulence genes and antimicrobial resistance profiles of Klebsiella pneumoniae isolated from urinary tract infections

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Randomized trial investigates virulence and resistance in Klebsiella pneumoniae, indicating serious clinical risks in UTIs.

This research examines the virulence and antibiotic resistance profiles of Klebsiella pneumoniae strains isolated from urinary tract infections.
Analyzed 10 K. pneumoniae isolates from UTIs for antibiotic susceptibility using disc diffusion method.
Classified strains as multidrug-resistant (MDR) if resistant to at least three antibiotic classes.
Utilized PCR to detect virulence and resistance genes including mrkA, blaSHV, and others.
All isolates were resistant to tetracycline, and 80% were resistant to ampicillin-sulbactam.
Sixty percent of isolates were classified as multidrug-resistant (MDR) and carried more virulence factors than non-MDR isolates.
Virulence genes mrkA and mrkD were found in 70% of isolates, while various resistance genes were detected in high percentages of the samples.

Maqsoodi et al. (2026) studied this question.

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