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June 19, 2026MicrobiologyOpenOpen Access

Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon

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Authors

MZMazen ZaylaaRFRayan FarhaJTJana Taleb

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Overview

Randomized trial explores interactions between virulence, resistance, and biofilm in Klebsiella pneumoniae, suggesting implications for infection control.

Key Points

  • Characterize resistance profiles, biofilm formation, and virulence genes in Klebsiella pneumoniae isolates causing urinary tract infections.
  • Analyzed 153 non-duplicate isolates from hospital and community settings in North Lebanon
  • Assessed antibiotic susceptibility, virulence gene presence, and biofilm formation
  • Investigated correlations between virulence factors and antimicrobial resistance
  • Higher resistance to cephalosporins noted in hospital-acquired and strong biofilm-forming isolates
  • ESBL production significantly more common in hospital-acquired and biofilm-forming strains
  • Strong biofilm formation primarily associated with classical K. pneumoniae and hospital-acquired infections

Cite This Study

Zaylaa et al. (2026) studied this question.

synapsesocial.com/papers/6a34dff765a5b0777af2ee1fhttps://doi.org/10.1002/mbo3.70336
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Biofilm, virulence, and ESBL-mediated resistance: unmasking <i>Klebsiella</i> spp. UTIs2026
  2. 2Antimicrobial resistance, biofilm formation, and molecular detection of efflux pump and biofilm genes among Klebsiella pneumoniae clinical isolates from Northern Jordan2024 · 14 citations
  3. 3Virulence genes and antimicrobial resistance profiles of Klebsiella pneumoniae isolated from urinary tract infections2026
  4. 4The Association Between Antibiotic Resistance and Biofilm Production in Klebsiella pneumoniae Isolated from Urinary Tract Infections.2024
  5. 5Carbapenem-resistant Klebsiella pneumoniae from clinical infections: a multifactorial analysis of resistance, virulence, and biofilm potential2025 · 4 citations