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August 13, 2026AntibioticsOpen Access

Associations of Biofilm Capacity with Antimicrobial Resistance and Virulence Genes in Klebsiella pneumoniae from Chickens in Henan, China, 2023–2025

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Overview

Randomized trial investigates biofilm and resistance in chickens, suggesting vigilant monitoring is needed.

Key Points

  • This study aimed to examine the relationship between biofilm formation, antimicrobial resistance, and virulence in K. pneumoniae isolates from chickens.
  • Isolates identified using blood agar culture, Gram staining, and MALDI-TOF MS.
  • Biofilm formation assessed by crystal violet assay; resistance and virulence genes analyzed through disk diffusion and PCR.
  • A total of 102 K. pneumoniae isolates from chickens were evaluated.
  • 81.4% of isolates were biofilm-forming strains; 15.7% exhibited hypermucoviscosity.
  • High resistance observed in 90.0% for penicillins; <10% for carbapenems, with 88.2% being multidrug-resistant.
  • Biofilm-forming isolates showed higher resistance to ceftiofur and florfenicol, with significant presence of virulence genes luxS, mrkD, and uge (p < 0.05).

Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/6a7d76062b0e0cff3f63f1efhttps://doi.org/10.3390/antibiotics15080767
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Biofilm Formation, Antibiotic Resistance, and Virulence Analysis of Human and Avian Origin Klebsiella pneumoniae from Jiangsu, China2025 · 7 citations
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  4. 4Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in <i>Klebsiella pneumoniae</i> Causing Urinary Tract Infections in North Lebanon2026
  5. 5Antimicrobial Resistance, Virulence, and Genomic Characteristics of <i>Klebsiella pneumoniae</i> Isolated From Four Host Sources in Northeast China2026