Why the study?
Does tight blood-pressure control prevent long-term cardiovascular and microvascular complications in patients with type 2 diabetes and hypertension after the intervention is stopped?
Population
884 patients with newly diagnosed type 2 diabetes mellitus and hypertension who underwent post-trial…
Comparison
Tight blood-pressure control regimen vs Less-tight blood-pressure control regimen
Design
Cohort, randomly assigned (during the initial trial phase)
Follow-up
10 years post-trial
Authors
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May indicate tight BP control benefits require continuation in T2D; leaves open whether sustained therapy alters long-term outcomes.
Does tight blood-pressure control prevent long-term cardiovascular and microvascular complications in patients with type 2 diabetes and hypertension after the intervention is stopped?
The benefits of tight blood pressure control in type 2 diabetes are not sustained once the tight control is stopped and blood pressure differences between groups disappear, highlighting the need for continuous BP management.
Holman et al. (2008) studied this question.
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