Relationship between mitral annular plane systolic excursion and left ventricular ejection fraction by modified Simpson’s method using point of care cardiac ultrasound: An observational analytical study

OBJECTIVE The objective of this study was to find the relationship between MAPSE and LVEF by modified Simpson's method using point of care cardiac ultrasound. DESIGN Prospective observational study. SETTING Intensive care unit. PATIENTS Seventy-five patients admitted to the intensive care unit were recruited for determining the relationship between MAPSE and LVEF by modified Simpson's method. It was validated in the second part in another 75 patients by comparing the result obtained from modified Simpson's method and the previously derived equation. INTERVENTIONS None. MEASUREMENTS MAPSE, LVEF from modified Simpson's method in part I. An equation was derived from a linear relationship between the two. In part II, the derived equation for calculation of LVEF from MAPSE was validated with respect to a previously described equation and LVEF obtained by modified Simpson's method. Bias and precision were calculated. Time taken for both the procedures was also noted. RESULTS MAPSE showed a strong correlation with LVEF calculated by modified Simpson's method. The linear equation obtained was LVEF = 3.27 x MAPSE (mm) + 18.79 (ρ = 0.761, R2 = 0.520). Time taken for calculation of MAPSE was quicker (51.47 ± 11.18 s) as compared to that by modified Simpson's method (192.27 ± 31.93 s; p < 0.001). The equation was found to be 89.33% accurate. A MAPSE of 10.325 mm, predicts EF > 50% with a sensitivity of 90.7% and 90.6% specificity. CONCLUSION MAPSE correlates well with the EF measured by modified Simpson's method. It is faster and provides an accurate estimation of ejection fraction.