Why the study?
What are the mechanisms predisposing to sudden arrhythmic death in patients with heart failure?
What are the mechanisms predisposing to sudden arrhythmic death in patients with heart failure?
This review summarizes the electrophysiological, neurohumoral, and genetic mechanisms underlying sudden arrhythmic death in heart failure.
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Underscores complexity of sudden death risk in heart failure; extends mechanistic framework while leaving open therapeutic translation.
Tomaselli et al. (2004) studied this question.
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