Key result
Infusion of saralasin acetate in a patient with intractable congestive cardiac failure increased cardiac output and decreased systemic and pulmonary vascular resistance.
Why the study?
Does saralasin acetate infusion improve hemodynamics in a patient with intractable congestive cardiac failure?
Case Report (n=1)
Does saralasin acetate infusion improve hemodynamics in a patient with intractable congestive cardiac failure?
Angiotensin II inhibition with saralasin acetate acutely improves hemodynamics in severe heart failure, suggesting a potential therapeutic role for this pathway.
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Hypothesis-generating in refractory HF; leaves open whether angiotensin II antagonism improves outcomes in controlled trials.
Haralambos Gavras (1977) conducted a case report in Intractable congestive cardiac failure secondary to renovascular hypertension and severe coronary artery disease (n=1). Saralasin acetate was evaluated on Hemodynamic parameters including cardiac output and vascular resistance. Infusion of saralasin acetate in a patient with intractable congestive cardiac failure increased cardiac output and decreased systemic and pulmonary vascular resistance.
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