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This study aims to analyze the research status and identify critical research hotspots of the systemic immune-inflammation index (SII).

May 14, 2026

Research status and hotspots of the systemic immune-inflammation index: A bibliometric analysis.

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Bibliometric analysis reveals significant research themes and trends in the systemic immune-inflammation index.

This study aims to analyze the research status and identify critical research hotspots of the systemic immune-inflammation index (SII).
Conducted a bibliometric analysis using the Web of Science database.
Analyzed annual publication trends with tools like Excel, VOSviewer, and CiteSpace.
Examined authorship, affiliations, countries, keywords, and co-cited references.
Included 2,763 publications authored by 15,148 authors, with 726 core authors comprising 4.79% of the total.
Leading countries contributing literature included China (1532), Turkey (641), and the USA (91).
Keywords indicated research focused predominantly on tumors and their prognostic implications.

Yu et al. (2026) studied this question.

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