What type of study is this?

This is a Systematic Review study (also classified as: Meta-Analysis).

August 25, 2025Frontiers in Cardiovascular MedicineOpen Access

Diagnostic and prognostic value of systemic immune-inflammation index for heart failure: a systematic review and meta-analysis

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Authors

JYJiajun YuUniversity of Science and Technology of China TZTian ZuoSecond Military Medical University SPSihan PengSun Yat-sen University

Discussion

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Implication

Systematic review reveals systemic immune-inflammation index significantly correlates with mortality in heart failure patients, suggesting its prognostic utility.

Key Points

Elevated systemic immune-inflammation index is associated with increased mortality risk in heart failure patients, underscoring its prognostic value.
In a meta-analysis of 15 studies with 77,917 patients, systemic immune-inflammation index showed no significant link to heart failure incidence but heightened mortality risk.
Sensitivity and subgroup analyses indicated robustness in the association between systemic immune-inflammation index and mortality, regardless of study design or sample size.
The findings highlight systemic immune-inflammation index's potential as a clinical biomarker for evaluating prognosis in heart failure patients.

Cite This Study

Yu et al. (2025) studied this question.

synapsesocial.com/papers/68af5f07ad7bf08b1eae1816 https://doi.org/10.3389/fcvm.2025.1499449

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Implication

Systematic review reveals systemic immune-inflammation index significantly correlates with mortality in heart failure patients, suggesting its prognostic utility.

Diagnostic and prognostic value of systemic immune-inflammation index for heart failure: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Diagnostic and prognostic value of systemic immune-inflammation index for heart failure: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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