Key result
In critically ill patients with congestive heart failure, a high systemic immune-inflammation index was independently associated with an increased risk of 30-day all-cause mortality (HR 1.23).
Why the study?
The study aimed to clarify the potential predictive significance of the Systemic immune-inflammation index in assessing the poor prognosis of critically ill patients with congestive heart failure.
Does a high systemic immune-inflammation index (SII) predict increased short-term mortality and MACEs in critically ill patients with congestive heart failure?
Population
4606 critically ill patients with CHF from the MIMIC-III database
Comparison
High vs low level of SII (tertiles)
Design
Retrospective cohort study
Follow-up
90 days
Authors
Loading...
Should not yet change ICU risk stratification in CHF; leaves open SII as a hypothesis-generating prognostic marker.
Cohort (n=4,606)
No
Does a high systemic immune-inflammation index (SII) predict increased short-term mortality and MACEs in critically ill patients with congestive heart failure?
Hazard Ratio: 1.23 (95% CI 1.04–1.45)
In critically ill patients with congestive heart failure, a high systemic immune-inflammation index (SII) is an independent predictor of increased 30-day, 90-day, and hospital mortality, as well as MACEs.
Tang et al. (2021) conducted a cohort in Congestive heart failure (n=4,606). Systemic immune-inflammation index (SII) vs. Low systemic immune-inflammation index (tertile 1) was evaluated on 30-day all-cause mortality (HR 1.23, 95% CI 1.04-1.45). In critically ill patients with congestive heart failure, a high systemic immune-inflammation index was independently associated with an increased risk of 30-day all-cause mortality (HR 1.23).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: