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May 1, 2026HLA

The Novel HLA Allele, HLA‐A*68:278 , Identified by Sequence‐Based Typing in a Chinese Individual

Ming Zhang Gang Shen Mingdi He Wangxia Li

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Key Points

The aim is to describe a new HLA allele identified in an individual through genetic typing.
Sequence-based typing was performed to analyze HLA alleles.
Focus was on identifying specific changes at the codon level.
HLA-A*68:278 was identified with a single nonsynonymous change at codon 245.
The change distinguishes it from HLA-A*68:02:01:01.

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Implication

Novel allele HLA-A*68:278 shows a different nonsynonymous change in exon 4 compared to HLA-A*68:02:01:01.

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Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a056751a550a87e60a1f569 https://doi.org/10.1111/tan.70749

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