Why the study?
The prognostic value of a reduced LVEF at admission in patients with takotsubo syndrome is not fully established.
Does LVEF <40% at admission predict worse in-hospital outcomes in patients with Takotsubo Syndrome?
Population
100 patients with TTS admitted to a CICU between 2012 and 2024
Comparison
LVEF <40% vs LVEF ≥40% at admission
Design
Retrospective observational study
Key result
LVEF <40% at admission in Takotsubo Syndrome was associated with greater need for dobutamine (21.2% vs 0%; p<0.0001) and norepinephrine (19.2% vs 2.1%; p=0.0035), but not higher in-hospital mortality.
Authors
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Reduced LVEF on admission in TTS does not worsen in-hospital mortality or recovery; leaves open longer-term prognostic value.
Observational (n=100)
Does LVEF <40% at admission predict worse in-hospital outcomes in patients with Takotsubo Syndrome?
In patients with Takotsubo Syndrome, an initial LVEF <40% is a marker of acute severity requiring more hemodynamic support, but does not predict worse in-hospital mortality or poorer LVEF recovery at discharge.
Sendra et al. (2026) conducted an observational in Takotsubo Syndrome (n=100). LVEF <40% at admission vs. LVEF ≥40% at admission was evaluated on In-hospital mortality and LVEF at discharge. LVEF <40% at admission in Takotsubo Syndrome was associated with greater need for dobutamine (21.2% vs 0%; p<0.0001) and norepinephrine (19.2% vs 2.1%; p=0.0035), but not higher in-hospital mortality.