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May 14, 2026SAGE Open Medical Case ReportsOpen Access

Uremic pancreatitis following routine initiation of losartan in advanced chronic kidney disease: A case report

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Authors

VYVictoria C. YanADAbhi DeverakondaAJAlex R. Jones

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Overview

Case report reveals uremic pancreatitis in a patient with advanced chronic kidney disease, indicating careful monitoring is needed when starting ARBs.

Key Points

  • To report a case of uremic pancreatitis following the initiation of losartan in a patient with advanced chronic kidney disease.
  • Described the clinical course of a 35-year-old man with stage 4 CKD and acute kidney injury.
  • Conducted laboratory studies to rule out other causes of pancreatitis, including imaging.
  • Monitored abdominal pain and pancreatic enzyme levels during treatment with hemodialysis.
  • The patient developed severe abdominal pain and elevated pancreatic enzymes following losartan initiation.
  • Improvement in abdominal pain and pancreatic enzyme levels was observed after hemodialysis.
  • Diagnosis of uremic pancreatitis was supported as no other causes were identified, highlighting this condition's rarity in earlier CKD stages.

Cite This Study

Yan et al. (2026) studied this question.

synapsesocial.com/papers/6a05684ea550a87e60a20ba6https://doi.org/10.1177/2050313x261449105
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Timing insights in losartan-induced pancreatitis: a clinical case report2026 · 1 citations
  2. 2Losartan-Associated Sub-fulminant Hepatitis: A Case Report2026
  3. 3REPEATED TRANSIENT ANURIA FOLLOWING LOSARTAN ADMINISTRATION IN A PATIENT WITH A SOLITARY KIDNEY2001 · 20 citations
  4. 4Losartan, an Angiotensin-II Receptor Antagonist, Retards the Progression of Advanced Renal Insufficiency2006 · 10 citations
  5. 5Can ACE Inhibitors and Angiotensin Receptor Blockers Be Detrimental in CKD Patients?2011 · 59 citations