The Prognostic Implication of Left Atrial Strain Parameters with Conventional Left Atrial Parameters for the Prediction of Adverse Outcomes in Asian Patients with Hypertrophic Cardiomyopathy—An Echocardiographic Study
Key result
LA strain outperforms conventional measures in predicting HF hospitalization and adverse events in HCM.
- P<0.001
Why the study?
Left atrial function can aid risk stratification in HCM, but the prognostic performance of left atrial strain compared with conventional left atrial measures in Asian patients needed investigation.
Does left atrial strain analysis improve prediction of adverse outcomes compared to conventional left atrial measures in Asian patients with hypertrophic cardiomyopathy?
Population
Asian patients with HCM
Comparison
Left atrial strain analysis vs conventional left atrial measures
Authors
Discussion
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Member takes
Overview
May aid HCM risk stratification beyond conventional measures; leaves open whether adoption should change practice without prospective validation.
Study Design
Type
Cohort
Structured PICO
Does left atrial strain analysis improve prediction of adverse outcomes compared to conventional left atrial measures in Asian patients with hypertrophic cardiomyopathy?
P
Population
Asian patients with hypertrophic cardiomyopathy (HCM)
I
Intervention
Left atrial strain analysis
C
Comparator
Conventional left atrial measures
O
Outcome
Heart failure hospitalization and a composite of adverse eventscomposite
Main Result
p-value: p=< 0.001
Left atrial strain analysis provides superior prognostic value compared to conventional left atrial parameters for predicting adverse outcomes in Asian patients with hypertrophic cardiomyopathy.
Cite This Study
Seah et al. (2025) conducted a cohort in Hypertrophic cardiomyopathy. Left atrial strain analysis vs. Conventional left atrial measures was evaluated on Heart failure hospitalization and a composite of adverse events (p=< 0.001). Left atrial strain analysis outperformed conventional left atrial measures by demonstrating an independent association with heart failure hospitalization and a composite of adverse events in patients with HCM.