Key result
Antihypertensive agents can induce regression of left ventricular hypertrophy, but the most effective drug class and long-term clinical benefits remain controversial and undocumented.
Why the study?
Do antihypertensive agents improve long-term clinical outcomes and ventricular function by inducing regression of left ventricular hypertrophy in patients with hypertension?
Population
Patients with hypertension and left ventricular hypertrophy (LVH)
Design
Review
Authors
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LVH regression with antihypertensives leaves optimal class and long-term outcomes unresolved; prospective trials needed before practice change.
Do antihypertensive agents improve long-term clinical outcomes and ventricular function by inducing regression of left ventricular hypertrophy in patients with hypertension?
This review emphasizes the ongoing uncertainty regarding which antihypertensive drug class is most effective for LVH regression and whether this reversal translates into definitive long-term clinical benefits.
Eselin et al. (1994) conducted a review in Hypertension and Left Ventricular Hypertrophy. Antihypertensive agents was evaluated. Antihypertensive agents can induce regression of left ventricular hypertrophy, but the most effective drug class and long-term clinical benefits remain controversial and undocumented.
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