Why the study?
Does ECG-gated MR imaging accurately quantify left ventricular mass in normal dogs and dogs with left ventricular hypertrophy compared to postmortem mass?
Population
Normal dogs and dogs with left ventricular hypertrophy
Comparison
ECG-gated MR imaging for quantitating left… vs Postmortem left ventricular mass
Design
Preclinical
Key result
ECG-gated MR imaging accurately quantified canine left ventricular mass, demonstrating a strong correlation with postmortem mass at both end diastole (r=0.94) and late systole (r=0.94).
Authors
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Supports ECG-gated MR for canine LV mass quantification; leaves open human translation.
Observational
Does ECG-gated MR imaging accurately quantify left ventricular mass in normal dogs and dogs with left ventricular hypertrophy compared to postmortem mass?
Effect estimate: r = 0.94
ECG-gated MR imaging provides an accurate and reproducible method for quantifying left ventricular mass in a canine model.
Caputo et al. (1987) conducted an observational in Normal dogs and dogs with left ventricular hypertrophy. ECG-gated MR imaging vs. Postmortem left ventricular mass was evaluated on Correlation between postmortem left ventricular mass and mass measured via MR images (r = 0.94). ECG-gated MR imaging accurately quantified canine left ventricular mass, demonstrating a strong correlation with postmortem mass at both end diastole (r=0.94) and late systole (r=0.94).