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November 1, 1988Radiology

Estimation of human myocardial mass with MR imaging.

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Why the study?

Does MR imaging accurately and reproducibly estimate left ventricular mass in humans?

Population

10 cadaver hearts and 40 human subjects

Comparison

Magnetic resonance imaging using ten short-axis… vs True left ventricular weight

Design

Other

Authors

JKJ. KatzMMM. C. MillikenJSJ. Stray‐Gundersen

Discussion

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Overview

MR imaging reproducibility supports research use for LV mass; leaves open larger validation before clinical adoption.

Key Points

  • This research aims to assess the accuracy and reproducibility of MR imaging for estimating left ventricular mass in humans.
  • Imaging of ten cadaver hearts to compare true left ventricular weight with MR imaging estimates.
  • In vivo assessment included 40 subjects with left ventricular mass measurement.
  • Analysis of intra- and interobserver variability in ten subjects.
  • Calculated left ventricular masses ranged from 156.4 to 319.3 g in vivo.
  • Intraobserver variability showed excellent correlation (r = 0.96, SEE = 11.1 g).
  • Interobserver variability also demonstrated strong correlation (r = 0.91, SEE = 17.8 g).

Structured PICO

Does MR imaging accurately and reproducibly estimate left ventricular mass in humans?

P
Population
10 cadaver hearts and 40 human subjects
I
Intervention
Magnetic resonance (MR) imaging using ten short-axis, end-diastolic images to estimate left ventricular mass
C
Comparator
True left ventricular weight (for the 10 cadaver hearts)
O
Outcome
Accuracy and reproducibility (intra- and interobserver variability) of left ventricular mass estimationsurrogate

MR imaging is a highly accurate and reproducible method for estimating left ventricular mass in vivo.

Cite This Study

Katz et al. (1988) studied this question.

synapsesocial.com/papers/6a10bb94acd1dbe06464521chttps://doi.org/10.1148/radiology.169.2.2971985
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Measurement of canine left ventricular mass by using MR imaging1987 · 69 citations
  2. 2Determination of left ventricular mass by magnetic resonance imaging in hearts deformed by acute infarction.1989 · 165 citations
  3. 3Measurement of left ventricular mass in rats using electrocardiogram-gated magnetic resonance imaging1990 · 38 citations
  4. 4Simultaneous and correlated detection of endocardial and epicardial borders on short-axis MR images for the measurement of left ventricular mass.1998 · 22 citations
  5. 5Magnetic resonance imaging compared to echocardiography to assess left ventricular mass in the hypertensive patient1995 · 367 citations