Rapid multislice spin echo MR imaging measured left ventricular mass in 15 minutes with good agreement to the standard single slice method (mean difference -1.72 g; 95% CI limits +/- 14%).
Cross-Sectional (n=16)
Does a rapid multislice spin echo MRI technique accurately measure left ventricular mass compared to single slice acquisitions in healthy volunteers?
A rapid multislice spin echo MRI technique provides accurate measurements of left ventricular mass in 15 minutes, comparable to longer single-slice methods.
Effect estimate: Mean difference -1.72 g (95% CI +/- 14% limits of agreement)
Absolute Event Rate: 212% vs 213%
Magnetic resonance (MR) imaging provides an accurate measurement of left ventricular mass but imaging time can be up to 45 min. We tested a more rapid multislice spin echo technique on 16 volunteers without evidence of heart disease. Multislice short axis spin echo images were acquired in up to three sets of five, clustered around end systole. Total imaging time was 15 min. Myocardial areas were summed and specific gravity was assumed. Comparison was made with multiple single acquisitions timed to end systole. There was good agreement between the two measurements of left ventricular mass. Mean (+/- standard deviation (sd), range) values were 212 g (+/- 41.71, 152 to 311) by the multislice method and 213 g (+/- 44.26, 155 to 317) by the single slice method. The mean difference (+/- sd of difference) between measurements was -1.72 +/- 14.89 g (95% confidence interval for limits of agreement was +/- 14%). We have therefore established a more rapid and accurate method of measuring left ventricular mass.
Forbat et al. (Sat,) conducted a cross-sectional in Healthy volunteers without evidence of heart disease (n=16). Rapid multislice spin echo MR imaging vs. Multiple single acquisitions (single slice method) was evaluated on Left ventricular mass (Mean difference -1.72 g, 95% CI +/- 14% limits of agreement). Rapid multislice spin echo MR imaging measured left ventricular mass in 15 minutes with good agreement to the standard single slice method (mean difference -1.72 g; 95% CI limits +/- 14%).
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