Why the study?
Does partial curarization and autonomic blockade alter cardiovascular responses to static exercise in humans?
Population
17 human subjects
Comparison
Partial curarization with tubocurarine and… vs Static handgrip exercise without curarization or…
Design
Other
Authors
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Hypothesis-generating for autonomic control of exercise responses; leaves open clinical translation pending confirmatory trials.
Does partial curarization and autonomic blockade alter cardiovascular responses to static exercise in humans?
The centrally generated heart rate response to static exercise is partly caused by vagal withdrawal, while blood pressure control exhibits greater redundancy and cannot be attenuated by sole alpha- or beta-adrenergic blockade.
Mitchell et al. (1989) studied this question.
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