Key result
Isolated syncope, reported by 3.0% of men and 3.5% of women, was not associated with any excess of stroke, myocardial infarction, or mortality during 26 years of follow-up.
Why the study?
Is isolated syncope associated with an increased risk of stroke, myocardial infarction, or mortality in a general adult population?
Population
5,209 adults (2,336 men and 2,873 women) aged 30 to 62 years at entry to the Framingham Study.
Comparison
Isolated syncope vs No isolated syncope (general cohort population)
Design
Cohort
Follow-up
26 years
Authors
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Isolated syncope may be benign in low-risk adults; leaves open validation in higher-risk groups or prospective cohorts.
Cohort (n=5,209)
Is isolated syncope associated with an increased risk of stroke, myocardial infarction, or mortality in a general adult population?
Isolated syncope in adults without prior cardiovascular or neurologic disease is benign and not associated with increased long-term cardiovascular morbidity or mortality.
Savage et al. (1985) conducted a cohort in Isolated syncope (n=5,209). Isolated syncope vs. No isolated syncope was evaluated on Stroke, myocardial infarction, all-cause or cardiovascular mortality. Isolated syncope, reported by 3.0% of men and 3.5% of women, was not associated with any excess of stroke, myocardial infarction, or mortality during 26 years of follow-up.
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