What is the clinical evidence from this study?

Study design: Observational. Population: Acute heart failure (n=1658). Primary outcome: In-hospital mortality.

What question did this study set out to answer?

To enhance understanding of acute heart failure epidemiology, management, and clinical outcomes in France.

November 27, 2012European Journal of Heart FailureOpen Access

Current Aspects of the Spectrum of Acute Heart Failure Syndromes in a Real-Life Setting: The OFICA Study

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Key result

Acute heart failure in a real-life setting was associated with an in-hospital mortality of 8.2%, with age, blood pressure, and creatinine identified as independent predictors.

Population

1,658 patients with unplanned hospitalizations because of acute heart failure in 170 hospitals throughout…

Design

Cross-sectional

Follow-up

in-hospital (median 13 days)

Authors

DLDamien LogeartHeart Failure & Transplant RIRichard IsnardHeart Failure & Transplant MRMatthieu Resche‐RigonHeart Failure / Cardiomyopathy

Discussion

Member takes

Implication

Reinforces acute HF severity in routine care; leaves open whether optimizing GDMT improves outcomes in heterogeneous populations.

Key Points

To enhance understanding of acute heart failure epidemiology, management, and clinical outcomes in France.
Conducted an observational survey in 170 hospitals over one day, capturing unplanned AHF hospitalizations
Included 1658 patients with a median age of 79 years and various clinical characteristics
Assessed management practices including natriuretic peptide testing and echocardiography usage.
In-hospital mortality rate was 8.2%, with age, blood pressure, and creatinine as independent predictors
36% of patients had preserved LVEF, linked to specific characteristics and lower severity
Treatment included ACE inhibitors/ARBs (78%), beta-blockers (67%), and aldosterone inhibitors (27%) at discharge.

Study Design

Type

Observational (n=1,658)

Multicenter

Yes

Structured PICO

Population

1,658 patients with unplanned hospitalizations because of acute heart failure (AHF) in 170 hospitals throughout France, median age 79 years, 55% male.

Outcome

Epidemiological data, management, and clinical outcome (including in-hospital mortality and length of stay)hard clinical

This real-world survey highlights the high severity and heterogeneity of acute heart failure, with an 8.2% in-hospital mortality rate and suboptimal use of guideline-directed medical therapy and devices at discharge.

Cite This Study

Logeart et al. (2012) conducted an observational in Acute heart failure (n=1,658). Acute heart failure in a real-life setting was associated with an in-hospital mortality of 8.2%, with age, blood pressure, and creatinine identified as independent predictors.

synapsesocial.com/papers/6a07b46644ff8ad339f69add https://doi.org/10.1093/eurjhf/hfs189

Topics

Heart failure HFrEF treatment Heart failure hospitalization HFpEF management

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Current Aspects of the Spectrum of Acute Heart Failure Syndromes in a Real-Life Setting: The OFICA Study

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Topics

Current Aspects of the Spectrum of Acute Heart Failure Syndromes in a Real-Life Setting: The OFICA Study

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

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Topics

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