Key result
Higher extracellular water ratio and diastolic dysfunction linked to worse cognition in elderly HF patients.
Cross-Sectional (n=43)
No
Body water distribution and diastolic heart function may influence cognitive function in elderly heart failure patients.
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Should not yet change practice in elderly HF; hypothesis-generating for fluid distribution and diastolic links to cognition.
In elderly patients with HF, cognitive function might be influenced by body water distribution and diastolic heart function.
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Futami et al. (2020) conducted a cross-sectional in Heart failure (n=43). Extracellular water/total body water (ECW/TBW) ratio was evaluated on Mini Mental State Examination (MMSE) score (B -180.17, 95% CI -311.49 to -48.85, p=0.009). In elderly patients with heart failure, cognitive function was negatively associated with the extracellular water to total body water ratio and measures of diastolic dysfunction.
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