Why the study?
Does a multiform pattern of premature ventricular complexes predict adverse cardiovascular events in patients undergoing ambulatory Holter monitoring?
Does a multiform pattern of premature ventricular complexes predict adverse cardiovascular events in patients undergoing ambulatory Holter monitoring?
In patients undergoing routine Holter monitoring, a multiform PVC pattern independently predicts a 4-fold increase in major adverse cardiovascular events or heart failure, whereas PVC frequency does not.
No takes yet. Share an insight, caveat, or question.
Multiform PVCs on Holter may flag higher risk but should not yet change practice; leaves open whether morphology adds independent value beyond frequency.
Ephrem et al. (2012) studied this question.
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