Why the study?
Is left ventricular diastolic function associated with exercise capacity in patients without ischemia or systolic dysfunction?
Population
2,867 patients undergoing exercise echocardiography using the Bruce protocol, excluding those with…
Design
Cross-sectional
Key result
Moderate/severe resting diastolic dysfunction was strongly associated with lower exercise capacity compared with normal function (-1.30 METs; 95% CI, -1.52 to -0.99; P < .001).
Authors
Loading...
Hypothesis-generating for diastolic dysfunction limiting exercise capacity in nonischemic preserved EF; prospective trials needed before clinical adoption.
Cross-Sectional (n=2,867)
No
Is left ventricular diastolic function associated with exercise capacity in patients without ischemia or systolic dysfunction?
Effect estimate: Beta -1.30 METs (95% CI -1.52 to -0.99)
p-value: p=<.001
Abnormalities of left ventricular diastolic function are independently associated with reduced exercise capacity in patients with normal ejection fraction and no ischemia.
Jasmine Grewal (2009) conducted a cross-sectional in Patients undergoing exercise echocardiography (n=2,867). Left ventricular diastolic dysfunction vs. Normal diastolic function was evaluated on Exercise capacity in metabolic equivalents (METs) (Beta -1.30 METs, 95% CI -1.52 to -0.99, p=<.001). Moderate/severe resting diastolic dysfunction was strongly associated with lower exercise capacity compared with normal function (-1.30 METs; 95% CI, -1.52 to -0.99; P < .001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: