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May 1, 1993Journal of Applied Physiology

Contribution of left ventricular diastolic function to exercise capacity in normal subjects

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Population

66 healthy subjects, comprising 57 normal sedentary volunteers and 9 endurance athletes.

Design

Cross-sectional

Authors

JVJean‐Louis VanoverscheldeBEB. EssamriRVR. Vanbutsele

Discussion

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Overview

Association between early diastolic filling and VO2 max may inform exercise physiology; cross-sectional data leave causality and clinical relevance open.

Structured PICO

P
Population
66 healthy subjects, comprising 57 normal sedentary volunteers (mean age 36 +/- 13 years, range 20-76 years) and 9 endurance athletes (mean age 37 +/- 8 years, range 26-51 years).
O
Outcome
Relationship of left ventricular functional indexes (assessed by two-dimensional and Doppler echocardiography) with VO2 max (assessed during multistage dynamic cycle exercise)surrogate

Left ventricular diastolic function, specifically early transmitral filling, strongly correlates with maximal exercise capacity in healthy subjects.

Cite This Study

Vanoverschelde et al. (1993) studied this question.

synapsesocial.com/papers/6a7d4fa6ec6dad7f5aaa138ehttps://doi.org/10.1152/jappl.1993.74.5.2225
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