What is the clinical evidence from this study?

Study design: Observational. Population: Left ventricular dysfunction after myocardial infarction (n=26). Intervention: Peak Vo2 ≥ 16 ml/kg per min vs. Peak Vo2 < 16 ml/kg per min. Primary outcome: Hemodynamic parameters and oxygen uptake (Vo2) during peak exercise.

What does this research mean for the field?

Left ventricular diastolic function parameters during peak exercise, such as tau, minimal LVP, minimal dP/dt, and EDP, are significantly correlated with peak oxygen uptake (Vo2) and serve as important determinants of exercise capacity in men with previous myocardial infarction. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

May 1, 2001Coronary Artery Disease

Relation between exercise capacity and left ventricular systolic versus diastolic function during exercise in patients after myocardial infarction

Q: What are the key findings of this study?

Peak Vo2 was significantly correlated with left ventricular diastolic function parameters (tau, minimal LVP, minimal dP/dt, EDP) during peak exercise in 26 men with previous myocardial infarction.

Q: What does this research mean for the field?

Left ventricular diastolic function parameters during peak exercise, such as tau, minimal LVP, minimal dP/dt, and EDP, are significantly correlated with peak oxygen uptake (Vo2) and serve as important determinants of exercise capacity in men with previous myocardial infarction. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Why the study?

Does left ventricular diastolic function during exercise correlate with exercise capacity in men after myocardial infarction?

Population

26 men who had previously suffered myocardial infarction, divided into two groups according to peak Vo2

Comparison

Symptom-limited exercise test with measurements… vs Patients with peak Vo2 < 16 ml/kg/min compared…

Design

Cross-sectional

Key result

Peak Vo2 was significantly correlated with left ventricular diastolic function parameters (tau, minimal LVP, minimal dP/dt, EDP) during peak exercise in 26 men with previous myocardial infarction.

Authors

TMToyohisa Miyashita YOYoshiaki Okano HTHiroshi Takaki

Discussion

Member takes

Overview

Diastolic reserve may limit exercise capacity post-MI; hypothesis-generating for targeted interventions.

Study Design

Type

Observational (n=26)

Structured PICO

Does left ventricular diastolic function during exercise correlate with exercise capacity in men after myocardial infarction?

Population

26 men who had previously suffered myocardial infarction, divided into two groups according to peak Vo2 (>= 16 ml/kg/min, n=13; < 16 ml/kg/min, n=13)

Intervention

Symptom-limited exercise test with measurements for hemodynamics and oxygen uptake (Vo2)

Comparator

Patients with peak Vo2 < 16 ml/kg/min compared to those with peak Vo2 >= 16 ml/kg/min

Outcome

Hemodynamic parameters (pulmonary arterial pressure, left ventricular and systemic arterial pressure, cardiac output, dP/dt, tau) at rest and during exercise, and their correlation with peak Vo2surrogate

Left ventricular diastolic reserve during exercise is an important determinant of exercise capacity in patients with left ventricular dysfunction after myocardial infarction.

Cite This Study

Miyashita et al. (2001) conducted an observational in Left ventricular dysfunction after myocardial infarction (n=26). Peak Vo2 ≥ 16 ml/kg per min vs. Peak Vo2 < 16 ml/kg per min was evaluated on Hemodynamic parameters and oxygen uptake (Vo2) during peak exercise. Peak Vo2 was significantly correlated with left ventricular diastolic function parameters (tau, minimal LVP, minimal dP/dt, EDP) during peak exercise in 26 men with previous myocardial infarction.

synapsesocial.com/papers/6a12e2e15bb7edc7189e6c67 https://doi.org/10.1097/00019501-200105000-00008

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May 1, 2001Coronary Artery Disease

Relation between exercise capacity and left ventricular systolic versus diastolic function during exercise in patients after myocardial infarction

View Full Paper

Ask AI

Bookmark

Why the study?

Does left ventricular diastolic function during exercise correlate with exercise capacity in men after myocardial infarction?

Population

26 men who had previously suffered myocardial infarction, divided into two groups according to peak Vo2

Comparison

Symptom-limited exercise test with measurements… vs Patients with peak Vo2 < 16 ml/kg/min compared…

Design

Cross-sectional

Key result

Peak Vo2 was significantly correlated with left ventricular diastolic function parameters (tau, minimal LVP, minimal dP/dt, EDP) during peak exercise in 26 men with previous myocardial infarction.

Authors

TMToyohisa Miyashita YOYoshiaki Okano HTHiroshi Takaki

Discussion

Member takes

Overview

Diastolic reserve may limit exercise capacity post-MI; hypothesis-generating for targeted interventions.

Study Design

Type

Observational (n=26)

Structured PICO

Does left ventricular diastolic function during exercise correlate with exercise capacity in men after myocardial infarction?

Population

26 men who had previously suffered myocardial infarction, divided into two groups according to peak Vo2 (>= 16 ml/kg/min, n=13; < 16 ml/kg/min, n=13)

Intervention

Symptom-limited exercise test with measurements for hemodynamics and oxygen uptake (Vo2)

Comparator

Patients with peak Vo2 < 16 ml/kg/min compared to those with peak Vo2 >= 16 ml/kg/min

Outcome

Left ventricular diastolic reserve during exercise is an important determinant of exercise capacity in patients with left ventricular dysfunction after myocardial infarction.

Cite This Study

synapsesocial.com/papers/6a12e2e15bb7edc7189e6c67 https://doi.org/10.1097/00019501-200105000-00008

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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