Key result
In patients with chronic heart failure, exercise capacity (VO2max) correlated significantly with the mitral inflow E/A ratio (R = -0.57, P<0.005) and isovolumic relaxation time (R = -0.48, P<0.01).
Why the study?
Does diastolic filling pattern correlate with exercise capacity in patients with chronic heart failure?
Population
40 patients with chronic heart failure secondary to ischaemic left ventricular impairment
Design
Cross-sectional
Authors
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Diastolic filling patterns correlated more with exercise capacity than systolic indices; leaves open whether they predict outcomes or guide therapy.
Cross-Sectional (n=40)
Does diastolic filling pattern correlate with exercise capacity in patients with chronic heart failure?
Effect estimate: R = -0.57
p-value: p=<0.005
Exercise capacity in chronic heart failure appears more closely related to abnormalities of diastolic filling patterns than to indices of systolic function.
Davies et al. (1992) conducted a cross-sectional in chronic heart failure (n=40). Diastolic filling indices was evaluated on Correlation of VO2max with mitral inflow E/A ratio (R = -0.57, p=<0.005). In patients with chronic heart failure, exercise capacity (VO2max) correlated significantly with the mitral inflow E/A ratio (R = -0.57, P<0.005) and isovolumic relaxation time (R = -0.48, P<0.01).
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