Key result
Radiofrequency ablation maintains similar long-term sinus rhythm in AF patients with and without concomitant cancer.
Why the study?
Comorbid cancer is increased in AF patients posing clinical management challenges, and whether cancer influences radiofrequency ablation decisions or its efficacy and safety was unclear.
Does radiofrequency catheter ablation maintain long-term sinus rhythm without increased recurrence in atrial fibrillation patients with cancer compared to those without cancer?
Cohort
Does radiofrequency catheter ablation maintain long-term sinus rhythm without increased recurrence in atrial fibrillation patients with cancer compared to those without cancer?
p-value: p== 0.62
Radiofrequency catheter ablation is a viable strategy for maintaining sinus rhythm in atrial fibrillation patients with concomitant cancer, as cancer does not appear to affect ablation decision-making or AF recurrence.
May support ablation decisions in AF with cancer; hypothesis-generating and requires prospective RCTs before practice change.
Background: The risk of comorbidity of cancer is increased in atrial fibrillation (AF) patients, which is a massive challenge for clinical management in cardiovascular settings. This study aimed to analyze whether cancer affects the decision of radiofrequency ablation and to explore the efficacy and safety of radiofrequency ablation in AF patients with cancer. Methods: We conducted a retrospective cohort study of patients who were first diagnosed AF and identified who were with cancer. The propensity score matching method was utilized to balance the differences between the cancer and non-cancer groups. Logistic regression analysis was used to study the related factors affecting the ablation of AF. Cox regression analysis was used to evaluate the effect of cancer on the recurrence of AF after radiofrequency ablation. Results: = 0.62). Conclusions: The combination of cancer did not affect the decision of patients to perform ablation therapy. Radiofrequency catheter ablation could be used as a strategy to maintain long-term sinus rhythm in patients with concomitant cancer without affecting AF recurrence.
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Wang et al. (2024) conducted a cohort in Atrial fibrillation and cancer. Radiofrequency catheter ablation vs. Non-cancer patients was evaluated on Recurrence of AF after radiofrequency ablation (p== 0.62). Radiofrequency catheter ablation maintained long-term sinus rhythm in atrial fibrillation patients with concomitant cancer without affecting AF recurrence compared to non-cancer patients (p=0.62).
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