Key result
Treadmill exercise in untrained rats increased maximal oxygen consumption to 83 ml/kg/min (a 5-fold increase over rest), with linear increases in heart rate, stroke volume, and oxygen extraction.
Why the study?
Does treadmill running alter cardiovascular parameters (Vo2, Q, HR, SV, Cao2-Cvo2) in untrained rats compared to rest?
Population
Untrained rats
Comparison
Treadmill running at various speeds (10-41 m/min) vs Rest
Design
Preclinical
Authors
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Hypothesis-generating for rodent exercise hemodynamics; leaves open translation to clinical cardiovascular responses.
Does treadmill running alter cardiovascular parameters (Vo2, Q, HR, SV, Cao2-Cvo2) in untrained rats compared to rest?
Heart rate, stroke volume, and oxygen extraction significantly contribute to the augmentation of oxygen consumption during exercise in untrained rats.
Gleeson et al. (1981) studied Healthy (untrained rats). Treadmill exercise vs. Rest was evaluated on Cardiovascular response (Vo2, Q, HR, SV, Cao2-Cvo2). Treadmill exercise in untrained rats increased maximal oxygen consumption to 83 ml/kg/min (a 5-fold increase over rest), with linear increases in heart rate, stroke volume, and oxygen extraction.
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