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July 1, 1975Journal of Applied Physiology

Effect of changes in arterial oxygen content on circulation and physical performance

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Why the study?

Does altering arterial oxygen content affect maximal oxygen consumption and hemodynamic parameters during exercise in human subjects?

Population

9 subjects

Comparison

Breathing 50% oxygen or rebreathing a carbon… vs Breathing room air (control) during exercise

Design

Other

Authors

BEBjörn EkblomPreventive CardiologyRHR HuotDouglas Mental Health University InstituteESE SteinJohn D. and Catherine T. MacArthur Foundation

Discussion

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Implication

Varying arterial oxygen content may influence exercise tolerance in cardiopulmonary patients; leaves open targeted oxygen strategies for optimizing aerobic capacity.

Structured PICO

Does altering arterial oxygen content affect maximal oxygen consumption and hemodynamic parameters during exercise in human subjects?

P
Population
9 subjects
I
Intervention
Breathing 50% oxygen (hyperoxia) or rebreathing a carbon monoxide gas mixture (hypoxia) during submaximal and maximal exercise
C
Comparator
Breathing room air (control) during exercise
O
Outcome
Maximal oxygen consumption (Vo2 max) and hemodynamic parameters (maximal cardiac output, stroke volume, heart rate)surrogate

Central circulation and transported oxygen are important limiting factors for human maximal aerobic power, as demonstrated by changes in Vo2 max with varying arterial oxygen content.

Cite This Study

Ekblom et al. (1975) studied this question.

synapsesocial.com/papers/6a203b89cb26ec8ce28fd3cehttps://doi.org/10.1152/jappl.1975.39.1.71
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Oxygen uptake, acid-base status, and performance with varied inspired oxygen fractions1980 · 132 citations
  2. 2Cerebrovascular responses to incremental exercise during hypobaric hypoxia: effect of oxygenation on maximal performance2007 · 154 citations
  3. 3Low-inspired oxygen condition on cardiorespiratory, metabolic functions and exercise performance2019
  4. 4IV. Oxygen Transport System Before and After Exposure to Chronic Hypoxia1990 · 45 citations
  5. 5Hyperoxia improves maximal exercise with the self-contained breathing apparatus (SCBA)2002 · 23 citations